A gastric acid secretion model
نویسندگان
چکیده
منابع مشابه
A model for integrative study of human gastric acid secretion.
We have developed a unique virtual human model of gastric acid secretion and its regulation in which food provides a driving force. Food stimulus triggers neural activity in central and enteric nervous systems and G cells to release gastrin, a critical stimulatory hormone. Gastrin stimulates enterochromaffin-like cells to release histamine, which, together with acetylcholine, stimulates acid se...
متن کاملGastric acid secretion.
PURPOSE OF REVIEW The present review summarizes the past year's literature, both clinical and basic science, regarding neuroendocrine and intracellular regulation of gastric acid secretion and proper use of antisecretory medications. RECENT FINDINGS Gastric acid kills microorganisms, modulates the gut microbiome, assists in digestion of protein, and facilitates absorption of iron, calcium, an...
متن کاملMaximal Gastric Acid Secretion in the Dog
As bstract. The reason for increased maximal acid secretory capacity in some patients with duodenal ulcer is uncertain. We postulated that chronically increased cephalic-vagal stimulation may be a cause of increased maximal acid output. To study this, we prepared six male, mongrel dogs with a vagally innervated gastric fistula, a vagally denervated fundic (Heidenhain) pouch, and a cervical esop...
متن کاملGastric acid secretion in chronic renal failure.
Contrary to the small amount of published evidence, but in accordance with clinical impression, we have found an increased incidence of peptic ulceration in people with chronic renal failure. Hyperacidic secretion in response to a standard pentagastrin test occurs in patients established on long-term dialysis treatment. The traditional liability of azotaemic patients to peptic ulceration seems ...
متن کاملAnion Requirements for Gastric Acid Secretion
The rate of hydrochloric acid production by isolated, bullfrog gastric mucosae depends critically on the supply of chloride ion to the serosal surface. Secretion of acid is negligible if chloride is completely replaced by glucuronate and gluconate ion. The experimental evidence indicates that the rate of acid secretion may be regarded as a reaction velocity, depending on chloride concentration ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1993
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(93)81036-1